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To determine MIC by dilution methods, antibiotics are also needed in a substance that requires preliminary dissolution to obtain a stock solution and then dilution to obtain an appropriate starting concentration. For most antibiotics, water is both a solvent and a diluter, including for most beta-lactams, fluoroquinolones, and aminoglycosides. Some require alcohol as a solvent, especially macrolides, chloramphenicol, and rifampicin, while others require a phosphate buffer or dimethyl sulfoxide DMSO. Get more information online mic recorder

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